The peculiarity is that mutations affect genes in different layers of the skin that encode proteins.
Depending on the severity and type of epidermolysis bullosa, there may be other, more severe symptoms that are considered on an individual basis. Symptoms often appear in the first hours of a newborn's life, so the qualifications and awareness of medical personnel will be important in the further treatment of the patient. Cause of epidermolysis bullosa.
At the same time, changes can occur not in one gene, but in several at once - often the disease disrupts the structure of more than 10 genes.
The main reason is a genetic predisposition to mutation of the genes responsible for encoding proteins, which is inherited from parents to children.
Autosomal dominant - characteristic of a simple type of epidermolysis bullosa. Autosomal recessive for borderline.Another type - dystrophic - can be inherited in both ways.